Human TSC22D3 Recombinant Protein (N-His) (HV509012)

Name: Human TSC22D3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HV509012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HV509012
Description	Recombinant Human TSC22D3 Protein, N-His (HV509012) expressed in E. coli, spanning Met1-Val134. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q99576
Protein length	Met1-Val134
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	16.97 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Delta sleep-inducing peptide immunoreactor, Glucocorticoid-induced leucine zipper protein, TSC-22-like protein, DSIPI, hDIP, TSC-22-related protein, GILZ, Protein DIP, TSC22D3, DSIP-immunoreactive peptide, TSC-22R, TSC22 domain family protein 3
Background	TSC22 domain family protein 3 (TSC22D3) is a ~14 kDa protein. Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation and thereby NFKB1 DNA-binding activities. In vitro, suppresses AP-1 transcription factor complex DNA-binding activities. 1. Asselin-Labat, ML. et al. (2004) Blood 104, 215-23. PMID: 15031210 2. Berrebi, D. et al. (2003) Blood 101, 729-38. PMID: 12393603 3. Ayroldi, E. et al. (2001) Blood 98, 743-53. PMID: 11468175
Note	For research use only.

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SDS-PAGE for Recombinant Human TSC22D3 Protein, N-His

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Datasheet

Human TSC22D3 Recombinant Protein (N-His).pdf

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Human TSC22D3 Recombinant Protein (N-His) (HV509012)

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