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Anti-Human TSPAN4 Polyclonal Antibody (HD423014)

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Aperçu
Numéro de catalogueHD423014
Description
Anti-Human TSPAN4 Polyclonal Antibody (HD423014) is a rabbit polyclonal antibody detecting TSPAN4. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human TSPAN4 (Tyr107-Asn201).
Cible NAG-2, NAG2, Novel antigen 2, TM4SF7, TSPAN4, Tetraspanin-4, Transmembrane 4 superfamily member 7, Tspan-4
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès O14817
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Contexte

Tetraspanin-4 (TSPAN4) is a ~26 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Plays an essential role in migrasome formation and migration on retracting fibers at the rear end of migrating cells. Migrasomes are cellular organelles that form as large vesicle-like structures on retraction fibers of migrating cells. Mechanistically, acts as a membrane curvature sensor and participates in stabilizing the migrasome structure in a late stage of biogenesis. May also play a regulatory role for the histamine H4 receptor/HRH4 without affecting histamine binding to HRH4 or signaling.

1. Huang, Y. et al. (2019) Nature cell biology 21, 991-1002. PMID: 31371828
2. Dharan, R. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119, e2208993119. PMID: 36252000
3. Dharan, R. et al. (2023) Nature communications 14, 1037. PMID: 36823145
4. Ma, X. et al. (2021) Biomolecules 11. PMID: 34439793
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human TSPAN4 Polyclonal Antibody

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