Anti-Human UCP3 Polyclonal Antibody (HX158014)

Name: Anti-Human UCP3 Polyclonal Antibody
Brand: abinScience
SKU: HX158014
Price: 96 USD
Availability: InStock

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Каталожный номер

HX158014

Описание

Anti-Human UCP3 Polyclonal Antibody (HX158014) is a rabbit polyclonal antibody detecting UCP3 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, Human, Sus scrofa, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human UCP3 (Met1-Phe312).

Цель

UCP3

Очистка

Purified by antigen affinity column.

Номер доступа

P55916

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Альтернативные названия

Mitochondrial uncoupling protein 3, UCP 3, Solute carrier family 25 member 9, UCP3, SLC25A9

Фон

Putative mitochondrial transporter UCP3 is a ~34 kDa protein. Putative transmembrane transporter that plays a role in mitochondrial metabolism via an as yet unclear mechanism. Originally, this mitochondrial protein was thought to act as a proton transmembrane transporter from the mitochondrial intermembrane space into the matrix, causing proton leaks through the inner mitochondrial membrane, thereby uncoupling mitochondrial membrane potential generation from ATP synthesis. However, this function is controversial and uncoupling may not be the function, or at least not the main function, but rather a consequence of more conventional metabolite transporter activity.

1. De Marchi, U. et al. (2011) The Journal of biological chemistry 286, 32533-41. PMID: 21775425

2. Codella, R. et al. (2023) FEBS letters 597, 309-319. PMID: 36114012

3. Echtay, KS. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 1416-21. PMID: 11171965

4. Zackova, M. et al. (2003) The Journal of biological chemistry 278, 20761-9. PMID: 12670931

5. Jaburek, M. et al. (2003) The Journal of biological chemistry 278, 25825-31. PMID: 12734183

6. Gong, DW. et al. (1997) The Journal of biological chemistry 272, 24129-32. PMID: 9305858

7. Cadenas, S. et al. (2002) The Journal of biological chemistry 277, 2773-8. PMID: 11707458

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-UCP3 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse liver lysate
Lane 2: Mouse heart lysate
Lane 3: Rat liver lysate
Lane 4: Rat heart lysate

Ссылки

Даташит

Anti-Human UCP3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

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Anti-Human UCP3 Polyclonal Antibody (HX158014)

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