Anti-Human VIPR1/VPAC1 Recombinant Antibody (23A11) (HB111107)

Name: Anti-Human VIPR1/VPAC1 Recombinant Antibody (23A11)
Brand: abinScience
SKU: HB111107
Price: 191 USD
Availability: InStock

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Número de catálogo	HB111107
Reactividad de especies	Human
Aplicaciones	FCM, SPR, WB
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
ID de clon	23A11
Objetivo	VIP-R-1, PACAP-R2, VIPR1, PACAP-R-2, Pituitary adenylate cyclase-activating polypeptide type II receptor, PACAP type II receptor, VPAC1, Vasoactive intestinal polypeptide receptor 1
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P32241
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.09% Sodium azide. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Vasoactive intestinal polypeptide receptor 1 (VIPR1/VPAC1) is a ~51 kDa protein. G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of ligand affinity VIP = PACAP27 > PACAP38. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. 1. Xu, Y. et al. (2022) Nature communications 13, 2272. PMID: 35477937 2. Piper, SJ. et al. (2022) Nature communications 13, 7013. PMID: 36385145 3. Couvineau, A. et al. (1994) Biochemical and biophysical research communications 200, 769-76. PMID: 8179610
Nota	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Human VIPR1/VPAC1 Antibody (23A11)

Referencias

Datasheet

Anti-Human VIPR1/VPAC1 Recombinant Antibody (23A11).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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