

| Número de catálogo | HC749014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human WNT3 Polyclonal Antibody (HC749014) is a rabbit polyclonal antibody detecting WNT3. Suitable for Human and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human WNT3 (Gly50-Lys355). | ||||||||
| Objetivo | INT4, Proto-oncogene Int-4 homolog, Proto-oncogene Wnt-3, WNT3 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P56703 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Proto-oncogene Wnt-3 (WNT3) is a ~39 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis. Required for normal formation of the apical ectodermal ridge. Required for normal embryonic development, and especially for limb development. 1. Mihara, E. et al. (2016) eLife 5. PMID: 26902720 2. Niemann, S. et al. (2004) American journal of human genetics 74, 558-63. PMID: 14872406 | ||||||||
| Nota | For research use only |
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