Human WNT3 Recombinant Protein (N-His) (HC749012)

Name: Human WNT3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC749012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC749012
Description	Recombinant Human WNT3 Protein, N-His (HC749012) expressed in E. coli, spanning Gly50-Lys355. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P56703
Protein length	Gly50-Lys355
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	36.75 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	INT4, Proto-oncogene Int-4 homolog, Proto-oncogene Wnt-3, WNT3
Background	Proto-oncogene Wnt-3 is a ~39 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis. Required for normal formation of the apical ectodermal ridge. Required for normal embryonic development, and especially for limb development. 1. Mihara, E. et al. (2016) eLife 5. PMID: 26902720 2. Niemann, S. et al. (2004) American journal of human genetics 74, 558-63. PMID: 14872406
Note	For research use only

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Datasheet

Human WNT3 Recombinant Protein (N-His).pdf

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Human WNT3 Recombinant Protein (N-His) (HC749012)

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