

| Número de catálogo | HT234013 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||
| Aplicaciones | ELISA, IF, IP | ||||
| Especie huésped | Mouse | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG2a, kappa | ||||
| ID de clon | C206 | ||||
| Objetivo | ZBTB7B, ZBTB15, ZFP67, ZNF857B, Zinc finger and BTB domain-containing protein 7B, Krueppel-related zinc finger protein cKrox, hcKrox, T-helper-inducing POZ/Krueppel-like factor, Zinc finger and BTB domain-containing protein 15, Zinc finger protein 67 homolog, Zinc finger protein 857B, Zinc finger protein Th-POK | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | O15156 | ||||
| RRID | Anti-Human ZBTB7B Antibody (C206) (abinScience Cat# HT234013, RRID:AB_3729219) |
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| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Fondo | Zinc finger and BTB domain-containing protein 7B (ZBTB7B) is a ~58 kDa protein. Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Exerts distinct biological functions in the mammary epithelial cells and T cells in a tissue-specific manner. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Cross-antagonism between ZBTB7B and CBF complexes are determinative to CD4 versus CD8 cell fate decision. 1. Widom, RL. et al. (1997) Gene 198, 407-20. PMID: 9370309 | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-Human ZBTB7B Antibody (C206)
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