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Anti-Human ZBTB7B Recombinant Antibody (C248) (HT234023)

Anti-Human ZBTB7B Recombinant Antibody (C248)
Anti-Human ZBTB7B Recombinant Antibody (C248)
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Overview
Catalog No.HT234023
Species reactivityHuman
ApplicationsELISA, IF, IP
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDC248
Clonality Monoclonal
Target ZBTB7B, ZBTB15, ZFP67, ZNF857B, Zinc finger and BTB domain-containing protein 7B, Krueppel-related zinc finger protein cKrox, hcKrox, T-helper-inducing POZ/Krueppel-like factor, Zinc finger and BTB domain-containing protein 15, Zinc finger protein 67 homolog, Zinc finger protein 857B, Zinc finger protein Th-POK
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession O15156
RRID

Anti-Human ZBTB7B Antibody (C248) (abinScience Cat# HT234023, RRID:AB_3729220)
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Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Zinc finger and BTB domain-containing protein 7B (ZBTB7B) is a ~58 kDa protein. Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Exerts distinct biological functions in the mammary epithelial cells and T cells in a tissue-specific manner. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Cross-antagonism between ZBTB7B and CBF complexes are determinative to CD4 versus CD8 cell fate decision.

1. Widom, RL. et al. (1997) Gene 198, 407-20. PMID: 9370309
Note For research use only.
Images
  • Anti-Human ZBTB7B Recombinant Antibody (C248)

    SDS-PAGE

    SDS-PAGE for Anti-Human ZBTB7B Antibody (C248)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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C₂ (Working Conc.)
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