

| Número de catálogo | HW705014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human ZEB1 Polyclonal Antibody (HW705014) is a rabbit polyclonal antibody detecting ZEB1 in ELISA, IHC, WB. Suitable for Chicken, Human, Mouse, and Rat.
Highlights
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| Reactividad de especies | Human, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human ZEB1 (Ser583-Glu643). | ||||||||
| Objetivo | Transcription factor 8, NIL-2-A zinc finger protein, Zinc finger E-box-binding homeobox 1, ZEB1, Negative regulator of IL2, TCF-8, TCF8, AREB6 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P37275 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Zinc finger E-box-binding homeobox 1 (ZEB1) is a ~124 kDa protein. Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-ZEB1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
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