

| Catalog No. | HW705022 |
|---|---|
| Description |
Recombinant Human ZEB1 Protein, N-His (HW705022) expressed in E. coli, spanning Tyr179-Leu295. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | P37275 |
| Protein length | Tyr179-Leu295 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 16.22 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | AREB6, NIL-2-A zinc finger protein, Negative regulator of IL2, TCF-8, TCF8, Transcription factor 8, ZEB1, Zinc finger E-box-binding homeobox 1 |
| Background | Zinc finger E-box-binding homeobox 1 is a ~124 kDa protein. Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. |
| Note | For research use only |
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