

| Numéro de catalogue | HW705014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ZEB1 Polyclonal Antibody (HW705014) is a rabbit polyclonal antibody detecting ZEB1 in ELISA, IHC, WB. Suitable for Chicken, Human, Mouse, and Rat.
Highlights
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| Reactivité des espèces | Human, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ZEB1 (Ser583-Glu643). | ||||||||
| Cible | Transcription factor 8, NIL-2-A zinc finger protein, Zinc finger E-box-binding homeobox 1, ZEB1, Negative regulator of IL2, TCF-8, TCF8, AREB6 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P37275 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Zinc finger E-box-binding homeobox 1 (ZEB1) is a ~124 kDa protein. Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-ZEB1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
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