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| カタログ番号 | HW705014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human ZEB1 Polyclonal Antibody (HW705014) is a rabbit polyclonal antibody detecting ZEB1 in ELISA, IHC, WB. Suitable for Chicken, Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ZEB1 (Ser583-Glu643). | ||||||||
| ターゲット | Transcription factor 8, NIL-2-A zinc finger protein, Zinc finger E-box-binding homeobox 1, ZEB1, Negative regulator of IL2, TCF-8, TCF8, AREB6 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P37275 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Zinc finger E-box-binding homeobox 1 (ZEB1) is a ~124 kDa protein. Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-ZEB1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
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