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Anti-Human ZNF445 Polyclonal Antibody (HD104014)

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Vista general
Número de catálogoHD104014
Descripción
Anti-Human ZNF445 Polyclonal Antibody (HD104014) is a rabbit polyclonal antibody detecting ZNF445. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human ZNF445 (Leu478-Glu925).
Objetivo ZFP445, ZKSCAN15, ZNF168, ZNF445, Zinc finger protein 168, Zinc finger protein 445, Zinc finger protein with KRAB and SCAN domains 15
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso P59923
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Zinc finger protein 445 (ZNF445) is a ~118 kDa protein. Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs). Acts together with ZFP57, but seems to be the major factor in human early embryonic imprinting maintenance. In contrast, in mice, ZFP57 plays the predominant role in imprinting maintenance.

1. Takahashi, N. et al. (2019) Genes & development 33, 49-54. PMID: 30602440
Nota For research use only
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Formula
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Working Solution
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