Human ZNF445 Recombinant Protein (N-His) (HD104012)

Name: Human ZNF445 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD104012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD104012
Description	Recombinant Human ZNF445 Protein, N-His (HD104012) expressed in E. coli, spanning Leu478-Glu925. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P59923
Protein length	Leu478-Glu925
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	55.29 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ZFP445, ZKSCAN15, ZNF168, ZNF445, Zinc finger protein 168, Zinc finger protein 445, Zinc finger protein with KRAB and SCAN domains 15
Background	Zinc finger protein 445 is a ~118 kDa protein. Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs). Acts together with ZFP57, but seems to be the major factor in human early embryonic imprinting maintenance. In contrast, in mice, ZFP57 plays the predominant role in imprinting maintenance. 1. Takahashi, N. et al. (2019) Genes & development 33, 49-54. PMID: 30602440
Note	For research use only

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Datasheet

Human ZNF445 Recombinant Protein (N-His).pdf

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Human ZNF445 Recombinant Protein (N-His) (HD104012)

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