Anti-Influenza A virus Matrix protein 2/M2e Recombinant Antibody (14C2) (VK736013)

Name: Anti-Influenza A virus Matrix protein 2/M2e Recombinant Antibody (14C2)
Brand: abinScience
SKU: VK736013
Price: 126 USD
Availability: InStock

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1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

VK736013

Reactivité des espèces

Influenza A virus (H1N1)

Applications

ELISA, IF, WB

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG1-kappa

ID de clone

14C2

Cible

Matrix protein 2, Proton channel protein M2, M

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P06821

RRID

Anti-Influenza A virus M/Matrix protein 2 Antibody (14C2) (abinScience Cat# VK736013, RRID:AB_3726905)
_x005F_x005F_x000D_

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Matrix protein 2 is a ~11 kDa protein. Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway.

Note

For research use only.

Images

Bioactivity

SEC-HPLC detection for Anti-Influenza A virus M/Matrix protein 2 Antibody (14C2).
SDS-PAGE

SDS-PAGE for Anti-Influenza A virus M/Matrix protein 2 Antibody (14C2).