Anti-Influenza A virus M/Matrix protein 2 Recombinant Antibody (SAA1442) (VK736023)

Name: Anti-Influenza A virus M/Matrix protein 2 Recombinant Antibody (SAA1442)
Brand: abinScience
SKU: VK736023
Price: 126 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

20ug
50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK736023

Species reactivity

Influenza A virus (H1N1)

Applications

ELISA, FCM, IF, WB

Host species

Human

Isotype

IgG1

Clone ID

SAA1442

Clonality

Monoclonal

Target

Matrix protein 2, Proton channel protein M2, M

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06821

RRID

Anti-Influenza A virus M/Matrix protein 2 Antibody (SAA1442) (abinScience Cat# VK736023, RRID:AB_3727015)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Matrix protein 2 is a ~11 kDa protein. Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway.

Note

For research use only.

Images