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| カタログ番号 | HC216014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-IQGAP1 Polyclonal Antibody (HC216014) is a rabbit polyclonal antibody detecting IQGAP1. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant IQGAP1 (Ser962-Ser1345). | ||||||||
| ターゲット | IQGAP1, KIAA0051, Ras GTPase-activating-like protein IQGAP1, p195 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 観測分子量 | 190 kDa | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P46940 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||||
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||||
| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ras GTPase-activating-like protein IQGAP1 is a ~189 kDa protein. Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Recruited to the cell cortex by interaction with ILK which allows it to cooperate with its effector DIAPH1 to locally stabilize microtubules and allow stable insertion of caveolae into the plasma membrane. Binds to activated CDC42 but does not stimulate its GTPase activity. Associates with calmodulin. May promote neurite outgrowth. 1. Li, Z. et al. (2005) The Journal of biological chemistry 280, 13871-8. PMID: 15695813 2. Johnson, M. et al. (2011) The international journal of biochemistry & cell biology 43, 65-73. PMID: 20883816 | ||||||||
| 注意事項 | For research use only |
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