Human IQGAP1 Recombinant Protein (N-His) (HC216012)

Name: Human IQGAP1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC216012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC216012
Description	Recombinant Human IQGAP1 Protein, N-His (HC216012) expressed in E. coli, spanning Ser962-Ser1345. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P46940
Protein length	Ser962-Ser1345
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	46.04 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	IQGAP1, KIAA0051, Ras GTPase-activating-like protein IQGAP1, p195
Background	Ras GTPase-activating-like protein IQGAP1 is a ~189 kDa protein. Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Recruited to the cell cortex by interaction with ILK which allows it to cooperate with its effector DIAPH1 to locally stabilize microtubules and allow stable insertion of caveolae into the plasma membrane. Binds to activated CDC42 but does not stimulate its GTPase activity. Associates with calmodulin. May promote neurite outgrowth. 1. Li, Z. et al. (2005) The Journal of biological chemistry 280, 13871-8. PMID: 15695813 2. Johnson, M. et al. (2011) The international journal of biochemistry & cell biology 43, 65-73. PMID: 20883816
Note	For research use only

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Datasheet

Human IQGAP1 Recombinant Protein (N-His).pdf

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Human IQGAP1 Recombinant Protein (N-His) (HC216012)

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