

| Каталожный номер | HC216014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-IQGAP1 Polyclonal Antibody (HC216014) is a rabbit polyclonal antibody detecting IQGAP1. Suitable for Human and Mouse.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant IQGAP1 (Ser962-Ser1345). | ||||||||
| Цель | IQGAP1, KIAA0051, Ras GTPase-activating-like protein IQGAP1, p195 | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Наблюдаемая молекулярная масса | 190 kDa | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P46940 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||||
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||||
| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Ras GTPase-activating-like protein IQGAP1 is a ~189 kDa protein. Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Recruited to the cell cortex by interaction with ILK which allows it to cooperate with its effector DIAPH1 to locally stabilize microtubules and allow stable insertion of caveolae into the plasma membrane. Binds to activated CDC42 but does not stimulate its GTPase activity. Associates with calmodulin. May promote neurite outgrowth. 1. Li, Z. et al. (2005) The Journal of biological chemistry 280, 13871-8. PMID: 15695813 2. Johnson, M. et al. (2011) The international journal of biochemistry & cell biology 43, 65-73. PMID: 20883816 | ||||||||
| Примечание | For research use only |
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