Anti-IRF4 Polyclonal Antibody (HS848014)

Name: Anti-IRF4 Polyclonal Antibody
Brand: abinScience
SKU: HS848014
Price: 168 USD
Availability: InStock

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Aperçu

Numéro de catalogue

HS848014

Description

Anti-IRF4 Polyclonal Antibody (HS848014) is a rabbit polyclonal antibody detecting IRF4 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human IRF4 (Glu130-Glu451).

Cible

IRF-4, NF-EM5, MUM1, LSIRF, IRF4, Multiple myeloma oncogene 1, Interferon regulatory factor 4, Lymphocyte-specific interferon regulatory factor

Purification

Purified by antigen affinity column.

Numéro d'accès

Q15306

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Interferon regulatory factor 4 (IRF4) is a ~51 kDa protein. Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.

Note

For research use only.

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