

| Número de catálogo | HC627033 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Human, Mouse, Rat | ||||
| Aplicaciones | IHC, WB | ||||
| Especie huésped | Mouse | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG2a, kappa | ||||
| ID de clon | N1/66 | ||||
| Objetivo | CAMKG, CAMK-II, CAMK, CAMK2G, CaM kinase II subunit gamma, CaMK-II subunit gamma, Calcium/calmodulin-dependent protein kinase type II subunit gamma | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | Q63633 | ||||
| RRID | Anti-KCC2 Antibody (N1/66) (abinScience Cat# HC627033, RRID:AB_3728371) |
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| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Fondo | Solute carrier family 12 member 5 (SLC12A5/KCC2) is a ~126 kDa protein. Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition. Involved in the regulation of dendritic spine formation and maturation. 1. Casula, S. et al. (2001) The Journal of biological chemistry 276, 41870-8. PMID: 11551954 2. Rivera, C. et al. (1999) Nature 397, 251-5. PMID: 9930699 3. Fiumelli, H. et al. (2013) Cerebral cortex (New York, N.Y. : 1991) 23, 378-88. PMID: 22345354 | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-KCC2 Antibody (N1/66)
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