Anti-KCC2 Recombinant Antibody (N1/12) (HC627013)

Name: Anti-KCC2 Recombinant Antibody (N1/12)
Brand: abinScience
SKU: HC627013
Price: 196 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC627013

Applications

IHC, WB

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

N1/12

Clonality

Monoclonal

Target

CAMKG, CAMK-II, CAMK, CAMK2G, CaM kinase II subunit gamma, CaMK-II subunit gamma, Calcium/calmodulin-dependent protein kinase type II subunit gamma

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q63633

RRID

Anti-KCC2 Antibody (N1/12) (abinScience Cat# HC627013, RRID:AB_3728369)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Solute carrier family 12 member 5 (SLC12A5/KCC2) is a ~126 kDa protein. Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition. Involved in the regulation of dendritic spine formation and maturation.

1. Casula, S. et al. (2001) The Journal of biological chemistry 276, 41870-8. PMID: 11551954

2. Rivera, C. et al. (1999) Nature 397, 251-5. PMID: 9930699

3. Fiumelli, H. et al. (2013) Cerebral cortex (New York, N.Y. : 1991) 23, 378-88. PMID: 22345354

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-KCC2 Antibody (N1/12)

References

Datasheet

Anti-KCC2 Recombinant Antibody (N1/12).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-KCC2 Recombinant Antibody (N1/12) (HC627013)

Overview

Images

References

Datasheet

SDS

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