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Anti-KCNJ10 Polyclonal Antibody (HX144014)

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Aperçu
Numéro de catalogueHX144014
Description
Anti-KCNJ10 Polyclonal Antibody (HX144014) is a rabbit polyclonal antibody detecting KCNJ10 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human KCNJ10 (Phe165-Val379).
Cible ATP-dependent inwardly rectifying potassium channel Kir4.1, KCNJ10, ATP-sensitive inward rectifier potassium channel 10, Inward rectifier K(+) channel Kir1.2, Potassium channel, inwardly rectifying subfamily J member 10
Purification Purified by antigen affinity column.
Numéro d'accès P78508
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

ATP-sensitive inward rectifier potassium channel 10 (KCNJ10) is a ~42 kDa protein. May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.

1. Shuck, ME. et al. (1997) The Journal of biological chemistry 272, 586-93. PMID: 8995301
2. Tanemoto, M. et al. (2014) FEBS letters 588, 899-905. PMID: 24561201
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-KCNJ10 Polyclonal Antibody

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