Anti-Kv1.2 K+ channel Recombinant Antibody (L76/36) (HB859023)

Anti-Kv1.2 K+ channel Antibody (L76/36) (abinScience Cat# HB859023, RRID:AB_3728140)
_x005F_x005F_x000D_ Copy Citation

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Potassium voltage-gated channel subfamily A member 2 (KCNA2/Kv1.2 K+ channel) is a ~56 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. Prevents aberrant action potential firing and regulates neuronal output. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, KCNA6, KCNA7, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel.