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Anti-LASV Nucleoprotein Polyclonal Antibody (VK810034)

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  • 50ug
  • 100ug
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Vista general
Número de catálogoVK810034
Descripción
Anti-Lassa virus/LASV Nucleoprotein Polyclonal Antibody (VK810034) is a rabbit polyclonal antibody detecting Nucleoprotein. Suitable for Lassa virus.
Reactividad de especiesLassa virus (LASV)
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Lassa virus/LASV Nucleoprotein (Met1-Leu569).
Objetivo EC:3.1.13.-, N, Nucleocapsid protein, Nucleoprotein, Protein N
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Purified by antigen affinity column.
Número de acceso P13699
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Nucleoprotein is a ~62 kDa protein. Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.

Nota For research use only
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Formula
C₁ × V₁ = C₂ × V₂
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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