Lassa virus/LASV Nucleoprotein Recombinant Protein (N-His&C-His) (VK810032)

Name: Lassa virus/LASV Nucleoprotein Recombinant Protein (N-His&C-His)
Brand: abinScience
SKU: VK810032
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	VK810032
Description	Recombinant Lassa virus/LASV Nucleoprotein, N-His&C-His (VK810032) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P13699
Protein length	Met1-Leu569
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Lassa virus (LASV)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	EC:3.1.13.-, N, Nucleocapsid protein, Nucleoprotein, Protein N
Background	Nucleoprotein is a ~62 kDa protein. Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.
Note	For research use only

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Datasheet

Lassa virus/LASV Nucleoprotein Recombinant Protein (N-His&C-His).pdf

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Lassa virus/LASV Nucleoprotein Recombinant Protein (N-His&C-His) (VK810032)

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Datasheet

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