Anti-LCMV RdRp/Protein L Polyclonal Antibody (VK147014)

Name: Anti-LCMV RdRp/Protein L Polyclonal Antibody
Brand: abinScience
SKU: VK147014
Price: 168 USD
Availability: InStock

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100ug

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

VK147014

Description

Anti-LCMV RdRp/Protein L Polyclonal Antibody (VK147014) is a rabbit polyclonal antibody detecting Protein L. Suitable for Lymphocytic choriomeningitis virus.

Reactivité des espèces

Lymphocytic choriomeningitis virus (LCMV)

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant LCMV RdRp/Protein L (Asp2-Lys196).

Cible

EC:2.7.7.48, EC:3.1.-.-, L, Large structural protein, Protein L, RNA-directed RNA polymerase L, Replicase, Transcriptase, cap-snatching endonuclease

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

P14240

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

RNA-directed RNA polymerase L (RdRp/Protein L) is a ~254 kDa protein. RNA-dependent RNA polymerase, which is responsible for the replication and transcription of the viral RNA genome using antigenomic RNA as an intermediate. During transcription, synthesizes subgenomic RNAs and assures their capping by a cap-snatching mechanism, which involves the endonuclease activity cleaving the host capped pre-mRNAs. These short capped RNAs are then used as primers for viral transcription. The 3'-end of subgenomic mRNAs molecules are heterogeneous and not polyadenylated. The replicase function is to direct synthesis of antigenomic and genomic RNA which are encapsidated and non capped.

1. Liu, L. et al. (2023) Protein & cell 14, 703-707. PMID: 37038286

Note

For research use only

Images

Reférences

Fiche technique

Anti-LCMV RdRp/Protein L Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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