

| Каталожный номер | VK147014 | ||||||||
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| Описание |
Anti-LCMV RdRp/Protein L Polyclonal Antibody (VK147014) is a rabbit polyclonal antibody detecting Protein L. Suitable for Lymphocytic choriomeningitis virus.
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| Реактивность видов | Lymphocytic choriomeningitis virus (LCMV) | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant LCMV RdRp/Protein L (Asp2-Lys196). | ||||||||
| Цель | EC:2.7.7.48, EC:3.1.-.-, L, Large structural protein, Protein L, RNA-directed RNA polymerase L, Replicase, Transcriptase, cap-snatching endonuclease | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P14240 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Фон | RNA-directed RNA polymerase L (RdRp/Protein L) is a ~254 kDa protein. RNA-dependent RNA polymerase, which is responsible for the replication and transcription of the viral RNA genome using antigenomic RNA as an intermediate. During transcription, synthesizes subgenomic RNAs and assures their capping by a cap-snatching mechanism, which involves the endonuclease activity cleaving the host capped pre-mRNAs. These short capped RNAs are then used as primers for viral transcription. The 3'-end of subgenomic mRNAs molecules are heterogeneous and not polyadenylated. The replicase function is to direct synthesis of antigenomic and genomic RNA which are encapsidated and non capped. 1. Liu, L. et al. (2023) Protein & cell 14, 703-707. PMID: 37038286 | ||||||||
| Примечание | For research use only |
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