Anti-Human MASP2 Polyclonal Antibody (HT020014)

Name: Anti-Human MASP2 Polyclonal Antibody
Brand: abinScience
SKU: HT020014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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SDS

Aperçu

Numéro de catalogue

HT020014

Description

Anti-MASP2 Polyclonal Antibody (HT020014) is a rabbit polyclonal antibody detecting MASP2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human MASP2 (Thr287-Phe686).

Cible

Mannan-binding lectin serine protease 2, Mannose-binding protein-associated serine protease 2, MASP-2, MBL-associated serine protease 2, MASP2

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Purified by antigen affinity column.

Numéro d'accès

O00187

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Mannan-binding lectin serine protease 2 (MASP2) is a ~75 kDa protein. Precursor of a serum protease that activates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The lectin complement system is activated following association of lectins, such as MBL2, FCN1, FCN2 or FCN3, to carbohydrates on the pathogen surface. MASP2 is cleaved and activated by MASP1 in response to lectin-binding to pathogen carbohydrates. Can activate prothrombin to thrombin.

1. Rossi, V. et al. (2001) The Journal of biological chemistry 276, 40880-7. PMID: 11527969

2. Héja, D. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10498-503. PMID: 22691502

3. Degn, SE. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 3957-69. PMID: 22966085

4. Matsushita, M. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 165, 2637-42. PMID: 10946292

5. Kidmose, RT. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 15425-30. PMID: 22949645

6. Thiel, S. et al. (1997) Nature 386, 506-10. PMID: 9087411

7. Valenzuela Leon, PC. et al. (2025) Journal of medicinal chemistry 68, 4663-4671. PMID: 39924859

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human MASP2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human MASP2 Polyclonal Antibody (HT020014)

Aperçu

Images

Reférences

Fiche technique

SDS