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Anti-MeV Non-structural protein V Polyclonal Antibody (VK815014)

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Vista general
Número de catálogoVK815014
Descripción
Anti-MeV Non-structural protein V Polyclonal Antibody (VK815014) is a rabbit polyclonal antibody detecting Non-structural protein V. Suitable for Measles virus.
Reactividad de especiesMeasles virus (MeV)
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant MeV Non-structural protein V (Met1-Gly231).
Objetivo Non-structural protein V, P/V
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso P0C774
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Non-structural protein V is a ~32 kDa protein. Plays an essential role in the inhibition of host immune response. Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway. Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state. Blocks the type I interferon signaling pathway by interacting with host TYK2 and thereby inhibiting downstream STAT1 and STAT2 phosphorylation. Blocks the type I interferon signaling pathway by disrupting the RIG-I signaling pathway.

1. Takeuchi, K. et al. (2003) FEBS letters 545, 177-82. PMID: 12804771
2. Parisien, JP. et al. (2009) Journal of virology 83, 7252-60. PMID: 19403670
3. Ramachandran, A. et al. (2008) Journal of virology 82, 8330-8. PMID: 18579593
4. Chinnakannan, SK. et al. (2013) PloS one 8, e57063. PMID: 23431397
5. Davis, ME. et al. (2014) Cell host & microbe 16, 19-30. PMID: 25011105
Nota For research use only
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-MeV Non-structural protein V Polyclonal Antibody

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