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| カタログ番号 | HB945014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-MMP9 Polyclonal Antibody (HB945014) is a rabbit polyclonal antibody detecting MMP9 in ELISA, IHC, WB, IF. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB, IF | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MMP9 (Val217-Asp390). | ||||||||
| ターゲット | Matrix metalloproteinase-9, CLG4B, GELB, 92 kDa type IV collagenase, 92 kDa gelatinase, Gelatinase B, MMP9, MMP-9 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P14780 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Matrix metalloproteinase-9 (MMP9) is a ~78 kDa protein. Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. 1. Takino, T. et al. (2003) Oncogene 22, 4617-26. PMID: 12879005 2. Tschesche, H. et al. (1992) Matrix (Stuttgart, Germany). Supplement 1, 245-55. PMID: 1480034 3. Wilhelm, SM. et al. (1989) The Journal of biological chemistry 264, 17213-21. PMID: 2551898 4. Jeon, S. et al. (2020) Circulation 142, 1736-1751. PMID: 32883094 | ||||||||
| 注意事項 | For research use only. |
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