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| カタログ番号 | MV615014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse CCL17/TARC Polyclonal Antibody (MV615014) is a rabbit polyclonal antibody detecting CCL17/TARC in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CCL17/TARC (Ala24-Pro93). | ||||||||
| ターゲット | C-C motif chemokine 17 (ABCD-2) (CC chemokine TARC) (Small-inducible cytokine A17) (Thymus and activation-regulated chemokine) | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9WUZ6 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | C-C motif chemokine 17 (CCL17/TARC) is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. 1. Lieberam, I. et al. (1999) European journal of immunology 29, 2684-94. PMID: 10508243 2. Schaniel, C. et al. (1999) European journal of immunology 29, 2934-47. PMID: 10508268 3. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438 4. Fülle, L. et al. (2018) Glia 66, 2246-2261. PMID: 30277599 5. Kato, T. et al. (2011) Experimental dermatology 20, 669-74. PMID: 21521373 | ||||||||
| 注意事項 | For research use only. |
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