

| Catalog No. | MV615022 |
|---|---|
| Description |
Recombinant Mouse CCL17/TARC Protein, N-GST & C-His (MV615022) expressed in E. coli, spanning Ala24-Pro93. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q9WUZ6 |
| Protein length | Ala24-Pro93 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Mus musculus (Mouse) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 36.10 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | C-C motif chemokine 17, CC chemokine TARC, CCL17, SCYA17, Small-inducible cytokine A17, TARC, Thymus and activation-regulated chemokine |
| Background | C-C motif chemokine 17 is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. 1. Lieberam, I. et al. (1999) European journal of immunology 29, 2684-94. PMID: 10508243 2. Schaniel, C. et al. (1999) European journal of immunology 29, 2934-47. PMID: 10508268 3. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438 4. Fülle, L. et al. (2018) Glia 66, 2246-2261. PMID: 30277599 5. Kato, T. et al. (2011) Experimental dermatology 20, 669-74. PMID: 21521373 |
| Note | For research use only |
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