Anti-Mouse CCL17/TARC Polyclonal Antibody (MV615014)

Name: Anti-Mouse CCL17/TARC Polyclonal Antibody
Brand: abinScience
SKU: MV615014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

MV615014

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CCL17/TARC (Ala24-Pro93).

Target

C-C motif chemokine 17 (ABCD-2) (CC chemokine TARC) (Small-inducible cytokine A17) (Thymus and activation-regulated chemokine)

Purification

Purified by antigen affinity column.

Accession

Q9WUZ6

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

C-C motif chemokine 17 (CCL17/TARC) is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions.

1. Lieberam, I. et al. (1999) European journal of immunology 29, 2684-94. PMID: 10508243

2. Schaniel, C. et al. (1999) European journal of immunology 29, 2934-47. PMID: 10508268

3. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438

4. Fülle, L. et al. (2018) Glia 66, 2246-2261. PMID: 30277599

5. Kato, T. et al. (2011) Experimental dermatology 20, 669-74. PMID: 21521373

Note

For research use only.

Images

References

Datasheet

Anti-Mouse CCL17/TARC Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-Mouse CCL17/TARC Polyclonal Antibody (MV615014)

Overview

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References

Datasheet

SDS

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