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Anti-Mouse Semaphorin 4D/CD100 Recombinant Antibody (SAA0332), APC (MV563137)

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Aperçu
Numéro de catalogueMV563137
Reactivité des espècesMouse
ApplicationsFCM
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneSAA0332
ConjugaisonAPC
Cible A8, Semaphorin-4D, GR3, BB18, SEMAJ, C9orf164, CD100, SEMA4D
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Numéro d'accès O09126
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Semaphorin-4D (CD100/SEMA4D) is a ~95 kDa protein. Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells.

1. Kuzirian, MS. et al. (2013) The Journal of neuroscience : the official journal of the Society for Neuroscience 33, 8961-73. PMID: 23699507
2. McDermott, JE. et al. (2018) Molecular and cellular neurosciences 92, 50-66. PMID: 29981480
3. Deng, S. et al. (2007) The Journal of neuroscience : the official journal of the Society for Neuroscience 27, 6333-47. PMID: 17554007
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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