Anti-Mouse CD100/SEMA4D Recombinant Antibody (SAA0332) (MV563107)

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Catalog No.	MV563107
Description	Anti-Mouse CD100/SEMA4D Antibody (SAA0332) [SAA0332] (MV563107) is a mouse monoclonal antibody detecting SEMA4D in FCM, FuncS, Neutralization. Suitable for Mouse. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Mouse
Applications	FCM, FuncS, Neutralization
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	SAA0332
Clonality	Monoclonal
Target	A8, Semaphorin-4D, GR3, BB18, SEMAJ, C9orf164, CD100, SEMA4D
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O09126
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Semaphorin-4D (CD100/SEMA4D) is a ~95 kDa protein. Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. 1. Kuzirian, MS. et al. (2013) The Journal of neuroscience : the official journal of the Society for Neuroscience 33, 8961-73. PMID: 23699507 2. McDermott, JE. et al. (2018) Molecular and cellular neurosciences 92, 50-66. PMID: 29981480 3. Deng, S. et al. (2007) The Journal of neuroscience : the official journal of the Society for Neuroscience 27, 6333-47. PMID: 17554007
Note	For research use only.

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MV563107-SDS-PAGE-1.jpg

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Anti-Mouse CD100/SEMA4D Recombinant Antibody (SAA0332).pdf

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Anti-Mouse CD100/SEMA4D Recombinant Antibody (SAA0332) (MV563107)

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