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Anti-Mouse CD11b/ITGAM Recombinant Antibody (F7), PerCP (MY474247)

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Vista general
Número de catálogoMY474247
Reactividad de especiesHuman, Mouse
AplicacionesELISA, FCM
ClonalidadMonoclonal
IsotipoDARPin
ID de clonF7
ConjugaciónPerCP
Objetivo Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, CD11b, Itgam
Nivel de endotoxinas Please contact with the lab for this information.
Número de acceso P05555
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo

Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

1. Wakselman, S. et al. (2008) The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 8138-43. PMID: 18685038
Nota For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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