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Anti-Mouse CD11b/ITGAM Recombinant Antibody (F7), PerCP (MY474247)

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Aperçu
Numéro de catalogueMY474247
Reactivité des espècesHuman, Mouse
ApplicationsELISA, FCM
ClonalitéMonoclonal
IsotypeDARPin
ID de cloneF7
ConjugaisonPerCP
Cible Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, CD11b, Itgam
Niveau d'endotoxines Please contact with the lab for this information.
Numéro d'accès P05555
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

1. Wakselman, S. et al. (2008) The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 8138-43. PMID: 18685038
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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