Anti-Mouse CD19 Recombinant Antibody (1D3), FITC (MB996117)

Name: Anti-Mouse CD19 Recombinant Antibody (1D3), FITC
Brand: abinScience
SKU: MB996117
Price: 196 USD
Availability: InStock

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Numéro de catalogue	MB996117
Reactivité des espèces	Mouse
Applications	FCM
Espèce hôte	Rat
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	1D3
Conjugaison	FITC
Cible	B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Produits associés	Rat IgG2a, kappa Recombinant Isotype Control Antibody (RTK2758), FITC
Numéro d'accès	P25918
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	B-lymphocyte antigen CD19 is a ~60 kDa protein. Functions as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. CD19 is the therapeutic target of tafasitamab (Monjuvi). 1. Wang, Y. et al. (2002) Immunity 17, 501-14. PMID: 12387743 2. Ishiura, N. et al. (2010) European journal of immunology 40, 1192-204. PMID: 20101619 3. Buhl, AM. et al. (1997) The Journal of experimental medicine 186, 1897-910. PMID: 9382888 4. Engel, P. et al. (1995) Immunity 3, 39-50. PMID: 7542548 5. Rickert, RC. et al. (1995) Nature 376, 352-5. PMID: 7543183 6. Sato, S. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 159, 3278-87. PMID: 9317126
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse CD19 Recombinant Antibody (1D3), FITC.pdf

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