Anti-Mouse CD21/CD35 Recombinant Antibody (7G6), FITC (MB939117)

Name: Anti-Mouse CD21/CD35 Recombinant Antibody (7G6), FITC
Brand: abinScience
SKU: MB939117
Price: 196 USD
Availability: InStock

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Aperçu

Numéro de catalogue	MB939117
Reactivité des espèces	Mouse
Applications	ELISA, FCM, WB
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	7G6
Conjugaison	FITC
Cible	CR1, CD35, Complement receptor type 1, CR1/CR2, C3DR, CD21, CD21/CD35, Cr-1, Cr-2
Niveau d'endotoxines	Please contact with the lab for this information.
Produits associés	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), FITC
Numéro d'accès	P19070
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	Complement receptor type 2 (CD21/CD35) is a ~112 kDa protein. Serves as a receptor for various ligands including complement component CD3d, HNRNPU OR IFNA1. When C3d is bound to antigens, attaches to C3d on B-cell surface and thereby facilitates the recognition and uptake of antigens by B-cells. This interaction enhances B-cell activation and subsequent immune responses. Forms a complex with several partners on the surface of B-cells including CD19, FCRL5 and CD81, to form the B-cell coreceptor complex that plays a crucial role in B-cell activation and signaling. Also induces specific intracellular signaling separately from the BCR and CD19 by activating the tyrosine kinase SRC, which then phosphorylates nucleolin/NCL and triggers AKT and GSK3 kinase activities in a SYK/CD19-independent manner.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse CD21/CD35 Recombinant Antibody (7G6), FITC.pdf

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