Anti-Mouse CD35/CR1/CD21b Recombinant Antibody (7G6) (MB625107)

Name: Anti-Mouse CD35/CR1/CD21b Recombinant Antibody (7G6)
Brand: abinScience
SKU: MB625107
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	MB625107
Species reactivity	Mouse
Applications	ELISA, FCM
Host species	Rat
Isotype	IgG2b, kappa
Clone ID	7G6
Clonality	Monoclonal
Target	Complement receptor type 1, C3b/C4b receptor, CD35, CR1, C3BR
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P19070
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Complement receptor type 2 (CD35/CR1) is a ~112 kDa protein. Serves as a receptor for various ligands including complement component CD3d, HNRNPU OR IFNA1. When C3d is bound to antigens, attaches to C3d on B-cell surface and thereby facilitates the recognition and uptake of antigens by B-cells. This interaction enhances B-cell activation and subsequent immune responses. Forms a complex with several partners on the surface of B-cells including CD19, FCRL5 and CD81, to form the B-cell coreceptor complex that plays a crucial role in B-cell activation and signaling. Also induces specific intracellular signaling separately from the BCR and CD19 by activating the tyrosine kinase SRC, which then phosphorylates nucleolin/NCL and triggers AKT and GSK3 kinase activities in a SYK/CD19-independent manner.
Note	For research use only.

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SDS-PAGE for Anti-Mouse CD35/CR1/CD21b Antibody (7G6)

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Datasheet

Anti-Mouse CD35/CR1/CD21b Recombinant Antibody (7G6).pdf

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Anti-Mouse CD35/CR1/CD21b Recombinant Antibody (7G6) (MB625107)

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Datasheet

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