Anti-Mouse CD21/CD35 Recombinant Antibody (7G6) (MB939107)

Name: Anti-Mouse CD21/CD35 Recombinant Antibody (7G6)
Brand: abinScience
SKU: MB939107
Price: 196 USD
Availability: InStock

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Обзор

Каталожный номер	MB939107
Реактивность видов	Mouse
Применения	ELISA, FCM, IHC, IP, WB
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG2a, kappa
ID клона	7G6
Цель	CR1, CD35, Complement receptor type 1, CR1/CR2, C3DR, CD21, CD21/CD35, Cr-1, Cr-2
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P19070
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон	Complement receptor type 2 (CD21/CD35) is a ~112 kDa protein. Serves as a receptor for various ligands including complement component CD3d, HNRNPU OR IFNA1. When C3d is bound to antigens, attaches to C3d on B-cell surface and thereby facilitates the recognition and uptake of antigens by B-cells. This interaction enhances B-cell activation and subsequent immune responses. Forms a complex with several partners on the surface of B-cells including CD19, FCRL5 and CD81, to form the B-cell coreceptor complex that plays a crucial role in B-cell activation and signaling. Also induces specific intracellular signaling separately from the BCR and CD19 by activating the tyrosine kinase SRC, which then phosphorylates nucleolin/NCL and triggers AKT and GSK3 kinase activities in a SYK/CD19-independent manner.
Примечание	For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Mouse CD21/CD35 Antibody (7G6)

Ссылки

Даташит

Anti-Mouse CD21/CD35 Recombinant Antibody (7G6).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

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