Anti-Mouse CD21/CR2 Polyclonal Antibody (MB939014)

Name: Anti-Mouse CD21/CR2 Polyclonal Antibody
Brand: abinScience
SKU: MB939014
Price: 168 USD
Availability: InStock

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SDS

Обзор

Каталожный номер

MB939014

Описание

Anti-Mouse CD21/CR2 Polyclonal Antibody (MB939014) is a rabbit polyclonal antibody detecting CD21. Suitable for Mouse.

Реактивность видов

Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Mouse CD21/CR2 (Ile12-Ala205).

Цель

C3DR, CD21, CR2, Complement C3d receptor, Complement receptor type 2, Cr2, EBV receptor, Epstein-Barr virus receptor

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P19070

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Фон

Complement receptor type 2 (CD21/CR2) is a ~112 kDa protein. Serves as a receptor for various ligands including complement component CD3d, HNRNPU OR IFNA1. When C3d is bound to antigens, attaches to C3d on B-cell surface and thereby facilitates the recognition and uptake of antigens by B-cells. This interaction enhances B-cell activation and subsequent immune responses. Forms a complex with several partners on the surface of B-cells including CD19, FCRL5 and CD81, to form the B-cell coreceptor complex that plays a crucial role in B-cell activation and signaling. Also induces specific intracellular signaling separately from the BCR and CD19 by activating the tyrosine kinase SRC, which then phosphorylates nucleolin/NCL and triggers AKT and GSK3 kinase activities in a SYK/CD19-independent manner.

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-Mouse CD21/CR2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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