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Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11) (MY282107)

Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11)
Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11)
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Aperçu
Numéro de catalogueMY282107
Reactivité des espècesMouse
ApplicationsELISA, FCM, Neutralization
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a
ID de clone2G11
Cible IGF2R, M6P/IGF2 receptor, 300 kDa mannose 6-phosphate receptor, IGF-II receptor, M6PR, CI-MPR, CD222, Insulin-like growth factor 2 receptor, MPR 300, M6P/IGF2R, MPRI, CI Man-6-P receptor, Insulin-like growth factor II receptor, Cation-independent mannose-6-phosphate receptor
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q07113
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Cation-independent mannose-6-phosphate receptor (CD222/IGF2R) is a ~273 kDa protein. Mediates the transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation by binding DPP4.

Note For research use only.
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  • Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD222/IGF2R Antibody (2G11)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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