Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11), PE (MY282127)

Name: Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11), PE
Brand: abinScience
SKU: MY282127
Price: 290 USD
Availability: InStock

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Overview

Catalog No.	MY282127
Species reactivity	Mouse
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a
Clone ID	2G11
Conjugation	PE
Clonality	Monoclonal
Target	IGF2R, M6P/IGF2 receptor, 300 kDa mannose 6-phosphate receptor, IGF-II receptor, M6PR, CI-MPR, CD222, Insulin-like growth factor 2 receptor, MPR 300, M6P/IGF2R, MPRI, CI Man-6-P receptor, Insulin-like growth factor II receptor, Cation-independent mannose-6-phosphate receptor
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), PE
Accession	Q07113
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Cation-independent mannose-6-phosphate receptor (CD222/IGF2R) is a ~273 kDa protein. Mediates the transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation by binding DPP4.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11), PE.pdf

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Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11), PE (MY282127)

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