Anti-Mouse CD244 Polyclonal Antibody (MV513014)

Name: Anti-Mouse CD244 Polyclonal Antibody
Brand: abinScience
SKU: MV513014
Price: 96 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

20ug
50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

MV513014

Descripción

Anti-Mouse CD244 Polyclonal Antibody (MV513014) is a rabbit polyclonal antibody detecting CD244 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Mouse CD244 (Asp24-Thr212).

Objetivo

SLAM family member 4, SLAMF4, h2B4, Signaling lymphocytic activation molecule 4, Natural killer cell receptor 2B4, NKR2B4, NAIL, NK cell type I receptor protein 2B4, CD244, NK cell activation-inducing ligand, 2B4

Purificación

Purified by antigen affinity column.

Número de acceso

Q07763

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Natural killer cell receptor 2B4 (CD244) is a ~44 kDa protein. Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Acts as activating natural killer (NK) cell receptor. Activating function implicates association with SH2D1A and FYN.

1. Lee, KM. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 4881-5. PMID: 12734329

2. Dong, Z. et al. (2009) Nature immunology 10, 973-80. PMID: 19648922

3. Wang, N. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 5683-7. PMID: 20962259

4. Garni-Wagner, BA. et al. (1993) Journal of immunology (Baltimore, Md. : 1950) 151, 60-70. PMID: 8326140

5. Chen, R. et al. (2004) Molecular and cellular biology 24, 5144-56. PMID: 15169881

6. Bloch-Queyrat, C. et al. (2005) The Journal of experimental medicine 202, 181-92. PMID: 15998796

7. Dong, Z. et al. (2012) Immunity 36, 974-85. PMID: 22683124

8. Lee, KM. et al. (2006) Blood 107, 3181-8. PMID: 15905190

9. Roncagalli, R. et al. (2005) Nature immunology 6, 1002-10. PMID: 16127454

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-CD244 polyclonal antibody at 1ug/mL on various samples.
Lane 1: MCF-7 cell lysate

Referencias

Datasheet

Anti-Mouse CD244 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo