Anti-Mouse CD244 Polyclonal Antibody (MV513014)

Name: Anti-Mouse CD244 Polyclonal Antibody
Brand: abinScience
SKU: MV513014
Price: 96 USD
Availability: InStock

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概要
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参考文献
データシート
SDS

概要

カタログ番号

MV513014

説明

Anti-Mouse CD244 Polyclonal Antibody (MV513014) is a rabbit polyclonal antibody detecting CD244 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

種反応性

Mouse

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Mouse CD244 (Asp24-Thr212).

ターゲット

SLAM family member 4, SLAMF4, h2B4, Signaling lymphocytic activation molecule 4, Natural killer cell receptor 2B4, NKR2B4, NAIL, NK cell type I receptor protein 2B4, CD244, NK cell activation-inducing ligand, 2B4

精製

Purified by antigen affinity column.

アクセッション番号

Q07763

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Natural killer cell receptor 2B4 (CD244) is a ~44 kDa protein. Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Acts as activating natural killer (NK) cell receptor. Activating function implicates association with SH2D1A and FYN.

1. Lee, KM. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 4881-5. PMID: 12734329

2. Dong, Z. et al. (2009) Nature immunology 10, 973-80. PMID: 19648922

3. Wang, N. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 5683-7. PMID: 20962259

4. Garni-Wagner, BA. et al. (1993) Journal of immunology (Baltimore, Md. : 1950) 151, 60-70. PMID: 8326140

5. Chen, R. et al. (2004) Molecular and cellular biology 24, 5144-56. PMID: 15169881

6. Bloch-Queyrat, C. et al. (2005) The Journal of experimental medicine 202, 181-92. PMID: 15998796

7. Dong, Z. et al. (2012) Immunity 36, 974-85. PMID: 22683124

8. Lee, KM. et al. (2006) Blood 107, 3181-8. PMID: 15905190

9. Roncagalli, R. et al. (2005) Nature immunology 6, 1002-10. PMID: 16127454

注意事項

For research use only.

イメージ

Western blot

Western blot analysis was performed using anti-CD244 polyclonal antibody at 1ug/mL on various samples.
Lane 1: MCF-7 cell lysate

参考文献

データシート

Anti-Mouse CD244 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

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アッセイキット

Anti-Mouse CD244 Polyclonal Antibody (MV513014)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ