Anti-Mouse Endosialin/CD248 Recombinant Antibody (G78), APC (MV681137)

Name: Anti-Mouse Endosialin/CD248 Recombinant Antibody (G78), APC
Brand: abinScience
SKU: MV681137
Price: 290 USD
Availability: InStock

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Número de catálogo	MV681137
Reactividad de especies	Human, Mouse
Aplicaciones	ELISA, FCM
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1, lambda
ID de clon	G78
Conjugación	APC
Objetivo	Endosialin, TEM1, CD164L1, Tumor endothelial marker 1, CD248
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Human IgG1, lambda Isotype Control antibody (HyHEL-10), APC
Número de acceso	Q91V98
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Endosialin (CD248) is a ~81 kDa protein. Cell surface glycoprotein involved in various biological processes including angiogenesis, immune response modulation, and tissue remodeling and repair. Participates in pericyte proliferation through positive modulation of the PDGF receptor signaling pathway. Acts as a scaffold for factor X, triggering allosteric changes and the spatial re-alignment of factor X with the TF-factor VIIa complex, thereby enhancing coagulation activation. Modulates the insulin signaling pathway by interacting with insulin receptor/INSR and by diminishing its capacity to be autophosphorylated in response to insulin. Also regulates LPS-induced inflammatory responses in macrophages by favoring production of proinflammatory cytokines. 1. Opavsky, R. et al. (2001) The Journal of biological chemistry 276, 38795-807. PMID: 11489895 2. Naylor, AJ. et al. (2014) PloS one 9, e107146. PMID: 25243742 3. Benedet, PO. et al. (2024) EBioMedicine 99, 104906. PMID: 38061240 4. Hong, YK. et al. (2019) The Journal of investigative dermatology 139, 2204-2214.e7. PMID: 30986375 5. Kapopara, PR. et al. (2021) Journal of thrombosis and haemostasis : JTH 19, 1932-1947. PMID: 33830628 6. Cheng, TL. et al. (2021) Translational research : the journal of laboratory and clinical medicine 232, 150-162. PMID: 33737161
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse Endosialin/CD248 Recombinant Antibody (G78), APC.pdf

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