Anti-Mouse Endosialin/CD248 Recombinant Antibody (G78), APC (MV681137)

Name: Anti-Mouse Endosialin/CD248 Recombinant Antibody (G78), APC
Brand: abinScience
SKU: MV681137
Price: 290 USD
Availability: InStock

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Обзор

Каталожный номер	MV681137
Реактивность видов	Human, Mouse
Применения	ELISA, FCM
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1, lambda
ID клона	G78
Конъюгация	APC
Цель	Endosialin, TEM1, CD164L1, Tumor endothelial marker 1, CD248
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Human IgG1, lambda Isotype Control antibody (HyHEL-10), APC
Номер доступа	Q91V98
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Endosialin (CD248) is a ~81 kDa protein. Cell surface glycoprotein involved in various biological processes including angiogenesis, immune response modulation, and tissue remodeling and repair. Participates in pericyte proliferation through positive modulation of the PDGF receptor signaling pathway. Acts as a scaffold for factor X, triggering allosteric changes and the spatial re-alignment of factor X with the TF-factor VIIa complex, thereby enhancing coagulation activation. Modulates the insulin signaling pathway by interacting with insulin receptor/INSR and by diminishing its capacity to be autophosphorylated in response to insulin. Also regulates LPS-induced inflammatory responses in macrophages by favoring production of proinflammatory cytokines. 1. Opavsky, R. et al. (2001) The Journal of biological chemistry 276, 38795-807. PMID: 11489895 2. Naylor, AJ. et al. (2014) PloS one 9, e107146. PMID: 25243742 3. Benedet, PO. et al. (2024) EBioMedicine 99, 104906. PMID: 38061240 4. Hong, YK. et al. (2019) The Journal of investigative dermatology 139, 2204-2214.e7. PMID: 30986375 5. Kapopara, PR. et al. (2021) Journal of thrombosis and haemostasis : JTH 19, 1932-1947. PMID: 33830628 6. Cheng, TL. et al. (2021) Translational research : the journal of laboratory and clinical medicine 232, 150-162. PMID: 33737161
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse Endosialin/CD248 Recombinant Antibody (G78), APC.pdf

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