

| Каталожный номер | MV612237 |
|---|---|
| Реактивность видов | Human, Mouse, Rat |
| Применения | FCM |
| Хозяинский вид | Rat |
| Клоональность | Monoclonal |
| Изотип | IgG1, kappa |
| ID клона | m276 |
| Конъюгация | APC |
| Цель | 4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Связанные продукты | Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), APC |
| Номер доступа | Q8VE98 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Фон | CD276 antigen (B7-H3) is a ~34 kDa protein. Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. CD276 is the therapeutic target of omburtamab (clinical). |
| Примечание | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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